Who He Dissed: 50 Cent
How He Dissed Him: At Hot 97's Summer Jam in 2005, Game took the stage and beat up a guy dressed in a gorilla outfit, which was seen as a shot at Game's mentor 50 Cent. Then, he solidified that sentiment by performing his hit song, "Hate It or Love It," and changing around some of the lines to reflect his unhappiness with the G-Unit general. "I ain't f------ with five-0," he rapped, "it's all starting to make sense!" Yes, it was. This was the start of a long, drawn-out feud between the two former friends.