Guns N' Roses
Song: "Sweet Child O' Mine"
Thank the curiosity of Axel Rose and Slash's guitar riff's for the rock master's biggest hit. "Sweet Child O Mine" was made by accident when Slash was practicing his riffs when Axel proclaimed that it would be their next single. The song catapulted their debut album, Appetite for Destruction (which is now 18 times platinum) to number 1 on the Billboard charts in 1987. Practice does make perfect after all.