The annual ceremony brought sweet soul to New York City's Apollo Theater on the music-dance program's 50th anniversary.
Doja Cat and H.E.R. are the most nominated women and Jay-Z breaks a record set by Quincy Jones.
This was the 26-year-old singer's debut at the American Music Awards.
Voting for all awards is now open globally via TikTok and fans can vote once per category per day by searching "AMAs" on the app.
New Music Friday: YoungBoy Never Broke Again, Ne-Yo, G-Eazy, D Smoke, Givēon, Tweet, Morray And More
This week's roundup also includes new bangers from Larry June, Dark Lo, Anthony Hamilton, Kari Faux, OT9 Beno, Westside Gunn, and more.
Rounding out the list of Billboard's top rap performers are Drake, Lil Baby, Kanye West, and Polo G.
Hosted by Doja Cat, tonight's show will air live at 8 p.m. ET/PT from the Barclay's Center in Brooklyn, N.Y. and feature performances by Lil Nas X, Chlöe, and Polo G.
The billboards confirm that Young Thug, Future, 21 Savage, Lil Baby, Ty Dolla $ign, Giveon, Yebba, Project Pat, Lil Durk, and more will appear on the album.