Scott's return kicks off on Sept. 17 at Zouk Nightclub in Resorts World Las Vegas.
The rapper ran through numerous hits from his catalog, including "Antidote," during his impromptu set.
The star-studded event included A-list singers, rappers, athletes, actors, and more.
"I've sold millions of records worldwide. And a lot of places don't have Soundscan so even some of my mixtapes, I've sold millions of," he said during the interview.
The singer holds the record for the longest run of any Black female artist's debut LP.
The new material fans are always begging for could be on the way.
This year's recipients include graduating seniors from 38 HBCUs.
The performance marks Scott's first televised performance following last year's Astroworld Festival tragedy.